Clinical Trial Matching
Identification of trials whose scientific rationale and eligibility criteria plausibly fit a specific case.
- Patients asking whether a relevant trial exists.
- Clinicians assessing trial options for a molecularly-defined case.
- Molecular profile and disease characteristics
- Prior therapy and current disease status
- Trial registries and eligibility criteria
- Geographic and practical feasibility
- A shortlist of trials with the rationale for each
- An assessment of plausible eligibility on the information available
- Notes on what would need confirming with the trial site
- Analysis and interpretation are provided to you and, where you wish, directly to your treating team — who continue to prescribe, administer and direct your treatment.
- The work sits alongside your treating oncologist and is designed to strengthen that relationship rather than sit outside it.
- It is built for considered review. Anything acute or time-critical belongs with your treating team or your local emergency service, who can act immediately.
- It sets out what the evidence supports and where it remains uncertain. It does not forecast how a particular cancer will respond.
- Trials are identified and assessed for plausible fit; eligibility itself is confirmed by the trial investigators, and enrolment is arranged with them.
Getting started
Nothing is charged for an enquiry, and scope is agreed in writing before any work starts.
Enquiries begin with a short message describing the situation and the question. From there, the documentation needed is agreed, and a scope and timeline are confirmed before any work starts.
The document checklist sets out what is typically needed. Missing items are worth identifying at the outset rather than mid-review.