Clinical service
Molecular Report Review
A detailed reading of a next-generation sequencing or molecular profiling report, including what the assay could and could not detect.
Who it is for
- Patients who have received an NGS report and cannot tell which findings matter.
- Clinicians wanting a second read of a complex molecular report.
What is reviewed
- The full variant list, including variants of uncertain significance
- Assay design, coverage and stated limits of detection
- Copy-number and structural findings where reported
- Tumour mutational burden, microsatellite status and other composite markers where reported
What is delivered
- Variant-by-variant interpretation with explicit evidence levels
- A clear separation of findings that are established, emerging, or unsupported
- Notes on what the assay would not have detected
- Questions worth raising with the reporting laboratory or treating team
How this works alongside your care
- Analysis and interpretation are provided to you and, where you wish, directly to your treating team — who continue to prescribe, administer and direct your treatment.
- The work sits alongside your treating oncologist and is designed to strengthen that relationship rather than sit outside it.
- It is built for considered review. Anything acute or time-critical belongs with your treating team or your local emergency service, who can act immediately.
- It sets out what the evidence supports and where it remains uncertain. It does not forecast how a particular cancer will respond.
- Re-analysis of raw sequencing data is possible where that data is supplied and its scope is agreed in advance.
How to begin
Getting started
Nothing is charged for an enquiry, and scope is agreed in writing before any work starts.
Enquiries begin with a short message describing the situation and the question. From there, the documentation needed is agreed, and a scope and timeline are confirmed before any work starts.
The document checklist sets out what is typically needed. Missing items are worth identifying at the outset rather than mid-review.
Other services
Precision Oncology Consultation
A structured discussion of the molecular and clinical picture in a cancer case, and of the questions it raises.
Cancer Second Opinion
An independent re-reading of the clinical, pathological and molecular record in a complex case.
Precision Oncology Analysis & Strategy
The flagship service: a structured review of the clinical, pathological, molecular and evidentiary dimensions of a complex cancer case.