Clinical service
Cancer Genetics & Hereditary Risk Review
Review of germline findings and family history, and of what they may mean for the patient and their relatives.
Who it is for
- Patients with a germline finding they want explained.
- Families with a pattern of cancer across relatives.
- Clinicians with a question about a germline variant’s interpretation.
What is reviewed
- Germline test reports and the variants classified within them
- Family history as documented
- Variant classification evidence and its basis
What is delivered
- Interpretation of germline findings and their classification
- Discussion of implications for relatives and cascade testing
- Surveillance and prevention questions to raise with the treating and genetics teams
How this works alongside your care
- Analysis and interpretation are provided to you and, where you wish, directly to your treating team — who continue to prescribe, administer and direct your treatment.
- The work sits alongside your treating oncologist and is designed to strengthen that relationship rather than sit outside it.
- It is built for considered review. Anything acute or time-critical belongs with your treating team or your local emergency service, who can act immediately.
- It sets out what the evidence supports and where it remains uncertain. It does not forecast how a particular cancer will respond.
- Where formal clinical genetics input is indicated, the review supports onward referral to an accredited service rather than substituting for it.
- Testing is recommended and specified where useful; the orders themselves are placed through your treating or genetics team.
How to begin
Getting started
Nothing is charged for an enquiry, and scope is agreed in writing before any work starts.
Enquiries begin with a short message describing the situation and the question. From there, the documentation needed is agreed, and a scope and timeline are confirmed before any work starts.
The document checklist sets out what is typically needed. Missing items are worth identifying at the outset rather than mid-review.
Other services
Precision Oncology Consultation
A structured discussion of the molecular and clinical picture in a cancer case, and of the questions it raises.
Molecular Report Review
A detailed reading of a next-generation sequencing or molecular profiling report, including what the assay could and could not detect.
Cancer Second Opinion
An independent re-reading of the clinical, pathological and molecular record in a complex case.